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Pandemic Planning Toolkit A resource to assist your organization in preparing for pandemic influenza
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How would a pandemic impact mortality?

A wide range of estimates15

Central to preparedness planning is estimating the mortality rates of the next pandemic. Experts' answers to this fundamental question have ranged from 2 million to more than 50 million. All of these predictions are scientifically grounded. The reasons for the wide range of estimates are numerous.
 
Some estimates are based on extrapolations from past pandemics, but significant details of these events are disputed, such as the true numbers of resulting deaths. The most precise predictions are based on the pandemic in 1968, but even in this case estimates vary from 1 million to 4 million deaths. Similarly, the number of deaths from the Spanish flu pandemic of 1918 is posited by different investigators to range from 20 million to well over 50 million.
 
Extrapolations are problematic because the world of today is a different place from the world of 1918. The impact of greatly improved nutrition and healthcare needs to be weighed against the contribution the increase in international travel would have on global spread. The specific characteristics of a future pandemic virus cannot be predicted. It may affect 20% to 50% of the total population. It is also unknown how pathogenic a novel virus would be.

Millions likely to be affected-even in a moderate pandemic15

Even in the best case scenarios of the next pandemic, 2 to 7 million people could die and tens of millions would require medical attention worldwide.
 
Two scenarios for the potential impact
of a flu pandemic on the US
12
 
Characteristic
Moderate (1958/68-like)
Severe
(1918-like)
Illness 90 million (30%) 90 million (30%)
Outpatient medical care 45 million (50%) 45 million (50%)
Hospitalization 865,000 9,900,000
ICU care 128,750 1,465,000
Mechanical ventilation 64,975 742,500
Deaths 209,000 1,903,000
 

Learn about the role vaccines will play in the event of a pandemic.



 
FOOTNOTE
12. Osterholm MT. Understanding pandemic influenza in the modern world. Paper presented at: Business Planning for Pandemic Influenza:
A National Summit; February 14, 2006; Minneapolis, Minn.
15. World Health Organization. Estimating the impact of the next influenza pandemic: enhancing preparedness. December 8, 2004. Available at: http://www.who.int/csr/disease/influenza/preparedness2004_12_08/en/. Accessed April 13, 2006.
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